Mirabegron is used alone or in combination with solifenacin (Vesicare) to treat overactive bladder (a condition in which the bladder muscles contract uncontrollably and cause frequent urination, urgent need to urinate, and inability to control urination). Mirabegron is in a class of medications called beta-3 adrenergic agonists. It works by relaxing the bladder muscles to prevent urgent, frequent, or uncontrolled urination. The generic alternative Mirabegron is available for sale. 

Mirabegron comes as an extended-release (long-acting) tablet to take by mouth. It is usually taken with or without food once a day. Take mirabegron at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take mirabegron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the extend-release tablets whole with water; do not split, chew, or crush them. Your doctor may increase your dose, depending on how well your symptoms are controlled and the side effects you experience. Talk to your doctor about how you are feeling during your treatment with mirabegron. Mirabegron controls the symptoms of overactive bladder but does not cure the condition. It may take 8 weeks or longer before you feel the full benefit of mirabegron. Continue to take mirabegron even if you feel well. Do not stop taking mirabegron without talking to your doctor. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Before taking mirabegron,

• tell your doctor and pharmacist if you are allergic to mirabegron, any other medications, or any of the ingredients in mirabegron extended-release tablets. Ask your pharmacist or check the patient information for a list of the ingredients.
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners) such as warfarin (Coumadin, Jantoven); desipramine (Norpramin); digoxin (Lanoxin); flecainide (Tambocor); other medications for overactive bladder such as darifenacin (Enablex),  and any other medication not listed here. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• tell your doctor if you have or have ever had bladder outlet obstruction (blockage at the base of the bladder that stops urine from flowing freely out of the bladder and causes difficulty emptying the bladder and/or a weak urine stream), high blood pressure, or kidney or liver disease.
• tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking mirabegron, call your doctor.
• you should know that your blood pressure may increase during your treatment with mirabegron. Your doctor will check your blood pressure regularly during your treatment.

Mirabegron may cause side effects including:

• headache
• dizziness
• dry mouth
• constipation
• back pain
• joint pain
• difficulty emptying the bladder, or weak urine stream (especially when used with solifenacin)

Tell your doctor if any of these symptoms are severe or do not go away. 

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

• signs of an allergic reaction including swelling of face, lips, tongue or throat, difficulty breathing or swallowing, hives, rash, itching
• difficult, painful, urgent, or frequent urination

Mirabegron may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Q: Why is Myrbetriq prescribed?

A: Myrbetriq is used to treat the symptoms of overactive bladder, such as frequent or urgent urination and urinary incontinence.

Q: Does Myrbetriq have a generic alternative?

A: Yes, Mirabegron (Generic) is available for purchase at a lower price than the brand.

Q: How long until I see the effects of Myrbetriq?

A: In trials, it took 4-8 weeks for some patients to start seeing an improvement in OAB symptoms. Your results may vary. 

Q: Are there any known drugs that interact with Myrbetriq?

A: Tell your doctor of all the medications you currently take or plan to take, especially: digoxin; flecainide; warfarin (Coumadin, Jantoven); propafenone; or thioridazine; metoprolol; or desipramine. This list is not complete.

Q: What if I miss a dose of Myrbetriq?

A: Skip the missed dose and continue your regular dosing schedule. Do not take more than one dose in one day and do not take a double dose to make up for a missed one.

Q: How should I store this medication?

A: Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).